From cells to chromatin: Capturing snapshots of genome organization with 5C technology
نویسندگان
چکیده
منابع مشابه
Chromatin plasticity and genome organization in pluripotent embryonic stem cells.
In search of the mechanisms that govern pluripotency and embryonic stem cell (ESC) self-renewal, a growing list of evidence highlights chromatin as a leading factor, controlling ESC maintenance and differentiation. In-depth investigation of chromatin in ESCs revealed distinct features, including DNA methylation, histone modifications, chromatin protein composition and nuclear architecture. Here...
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Comparative studies have provided the basis for some of the most important discoveries in biology. The study of differences, whether at the level of gene alleles or living kingdoms, has shown the critical features and function of most biological structures. The framework for comparative studies of organisms was perhaps laid out by the earliest taxonomists and medics: Dioscorides (80) and others...
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chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...
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ژورنال
عنوان ژورنال: Methods
سال: 2012
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2012.10.011